Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339292 | 0.93 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL8345831 | 0.85 | RAB9A (0.86) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL12402761 | 0.82 | RAB9A (0.69) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL28931086 | 0.81 | TRPM8 (0.58) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL10237187 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL2885708 | 0.80 | TRPM8 (0.78) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL8345120 | 0.80 | MAPT (0.57) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL8339659 | 0.79 | TRPM8 (0.73) | SMN1; SMN2RAB9ANPC1KDM4EGAA | |
| SCHEMBL5255659 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL2069278 | 0.78 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |