Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221676 | 0.85 | ALDH1A1 (0.36) | TDP1ALDH1A1TSHR | |
| SCHEMBL8348640 | 0.81 | ALDH1A1 (0.38) | HDAC8ALDH1A1TSHR | |
| SCHEMBL631423 | 0.80 | CYP3A4 (0.35) | TP53TDP1ALDH1A1TSHR | |
| SCHEMBL8892338 | 0.78 | CCNB2 (0.40) | ALDH1A1 | |
| SCHEMBL840464 | 0.76 | ADRB1 (0.45) | ALDH1A1TSHR | |
| SCHEMBL7310726 | 0.76 | IDO1 (0.39) | ALDH1A1 | |
| SCHEMBL7124643 | 0.75 | SLC6A2 (0.32) | — | |
| SCHEMBL5202527 | 0.73 | ENPP2 (0.34) | TSHR | |
| SCHEMBL481290 | 0.73 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL4380249 | 0.73 | PNMT (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932675-A | Free-radical chain transfer polymerization process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-08-03 | — | — | US | disclosed |
| US-5874511-A | CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-23 | — | — | US | disclosed |