Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344728 | 0.87 | HPSE (0.56) | KMT2AMEN1FFAR1HPSEPOLB | |
| Amsilarotene SCHEMBL1133175 | 0.86 | MEN1 (0.58) | KMT2AMEN1FFAR1PKMHPSE | |
| SCHEMBL9067770 | 0.84 | KMT2A (1.00) | KMT2AMEN1FFAR1PKML3MBTL1 | |
| SCHEMBL2058359 | 0.82 | KMT2A (0.96) | KMT2AMEN1FFAR1PKML3MBTL1 | |
| SCHEMBL8018938 | 0.81 | ACHE (0.62) | KMT2AMEN1L3MBTL1POLBTP53 | |
| SCHEMBL7822889 | 0.80 | MEN1 (0.78) | KMT2AMEN1FFAR1PKML3MBTL1 | |
| Hydrochloric Acid SCHEMBL10926742 | 0.79 | ACHE (0.61) | KMT2AMEN1L3MBTL1POLBTP53 | |
| SCHEMBL7610237 | 0.78 | MEN1 (0.53) | KMT2AMEN1FFAR1PKML3MBTL1 | |
| SCHEMBL3844305 | 0.77 | NPC1 (0.49) | KMT2AMEN1FFAR1PKMPOLB | |
| SCHEMBL3659600 | 0.77 | FFAR1 (0.89) | KMT2AMEN1FFAR1HPSEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36477-E | 4-(3,5-BIS(TRIMETHYLSILYLPHENYL)CARBOXAMIDO)BENZOIC ACID; DIFFERENTIATION-INDUCING REAGENT OR CELLS; ANTICARCINOGENTIC, -TUMOR,-INFLAMMATORY AND -PROLIFERATIVE AGENTS; PSORIASIS; LEUKEMIA; IMMUNOLOGY | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0337176-B1 | Novel benzoic acid derivatives and process for preparing the same | SHUDO KOICHI (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5155249-A | Differentiating neoplastic cells, treating psoriasis, immune or inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| US-5081271-A | Differentiation-inducing agent for neoplastic cells; therapeutic agent for psoriasis or immune and inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0337176-A2 | Novel benzoic acid derivatives and process for preparing the same | Shudo, Koichi, Prof. Dr. (JP) | 1989-10-18 | — | — | EP | disclosed |