Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344988 | 0.87 | KMT2A (0.71) | HPSEKMT2AMEN1POLBTP53 | |
| SCHEMBL7610237 | 0.86 | MEN1 (0.53) | HPSEKMT2AMEN1POLBTP53 | |
| SCHEMBL8345183 | 0.85 | RAB9A (0.62) | KCNK9KMT2AMEN1TP53HPGD | |
| SCHEMBL28409827 | 0.84 | KCNK3 (0.78) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL13066001 | 0.81 | TOP1 (0.46) | KCNK9KCNK3KMT2AMEN1TP53 | |
| SCHEMBL13065753 | 0.80 | FADS1 (0.47) | KCNK9KCNK3KMT2AMEN1POLB | |
| SCHEMBL8462114 | 0.80 | KMT2A (0.69) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL8461683 | 0.80 | MEN1 (0.73) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL9249052 | 0.79 | HPSE (0.84) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| Amsilarotene SCHEMBL1133175 | 0.78 | MEN1 (0.58) | HPSEKMT2AMEN1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155249-A | Differentiating neoplastic cells, treating psoriasis, immune or inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | claimed |
| JP-1249783-A | — | — | None | — | — | JP | disclosed |
| US-RE36477-E | 4-(3,5-BIS(TRIMETHYLSILYLPHENYL)CARBOXAMIDO)BENZOIC ACID; DIFFERENTIATION-INDUCING REAGENT OR CELLS; ANTICARCINOGENTIC, -TUMOR,-INFLAMMATORY AND -PROLIFERATIVE AGENTS; PSORIASIS; LEUKEMIA; IMMUNOLOGY | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0337176-B1 | Novel benzoic acid derivatives and process for preparing the same | SHUDO KOICHI (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5155249-A | Differentiating neoplastic cells, treating psoriasis, immune or inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| US-5081271-A | Differentiation-inducing agent for neoplastic cells; therapeutic agent for psoriasis or immune and inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0337176-A2 | Novel benzoic acid derivatives and process for preparing the same | Shudo, Koichi, Prof. Dr. (JP) | 1989-10-18 | — | — | EP | disclosed |
| JP-H01249783-A | NOVEL BENZOIC ACID DERIVATIVE AND PRODUCTION THEREOF | SHUDO KOICHI | 1989-10-05 | — | — | JP | disclosed |