Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058359 | 0.98 | KMT2A (0.96) | KMT2AMEN1L3MBTL1PKMFFAR1 | |
| SCHEMBL28595821 | 0.92 | KMT2A (0.84) | KMT2AMEN1L3MBTL1PKMFFAR1 | |
| SCHEMBL6242641 | 0.90 | MEN1 (0.81) | KMT2AMEN1L3MBTL1PKMFFAR1 | |
| SCHEMBL11474161 | 0.89 | KMT2A (0.79) | KMT2AMEN1L3MBTL1PKMFFAR1 | |
| SCHEMBL14715851 | 0.88 | KMT2A (0.79) | KMT2AMEN1L3MBTL1PKMTP53 | |
| SCHEMBL3659600 | 0.88 | FFAR1 (0.89) | KMT2AMEN1FFAR1HPSEHDAC2 | |
| SCHEMBL6866138 | 0.88 | KMT2A (0.78) | KMT2AMEN1L3MBTL1PKMFFAR1 | |
| SCHEMBL13802448 | 0.88 | MEN1 (0.78) | KMT2AMEN1L3MBTL1PKMFFAR1 | |
| SCHEMBL7822889 | 0.88 | MEN1 (0.78) | KMT2AMEN1L3MBTL1PKMFFAR1 | |
| SCHEMBL6802691 | 0.88 | KMT2A (0.78) | KMT2AMEN1L3MBTL1PKMFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| US-5493022-A | Brightener and light stabilizer salts | SANDOZ LTD. (CH) | 1996-02-20 | — | — | US | disclosed |
| EP-0451228-B1 | BRIGHTENING AND LIGHT-STABILIZING SALTS | SANDOZ AG (DE) | 1994-12-28 | — | — | EP | disclosed |
| US-5316553-A | Dyestuffs for the dyeing of synthetic polyamides | SANDOZ LTD. (CH) | 1994-05-31 | — | — | US | disclosed |
| EP-0451228-A1 | BRIGHTENING AND LIGHT-STABILIZING SALTS. | SANDOZ AG (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-5037448-A | Processes for the mass dyeing of synthetic polyamides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| WO-1991004987-A1 | BRIGHTENING AND LIGHT-STABILIZING SALTS | SANDOZ LTD. (CH) | 1991-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | HMOX1, HMOX2, PPOX | KMT2A 3310/4885MEN1 4396/4885L3MBTL1 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.