Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | RARA | P10276 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.50 |
| ▸ | RARG | P13631 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610237 | 0.89 | MEN1 (0.53) | MEN1KMT2AMITFFFAR1CA12 | |
| SCHEMBL8344988 | 0.86 | KMT2A (0.71) | MEN1KMT2AMITFFFAR1CYP26A1 | |
| SCHEMBL13027031 | 0.85 | NPC1 (0.42) | MEN1KMT2AFFAR1NPC1RAB9A | |
| SCHEMBL18123264 | 0.84 | ALDH1A1 (0.49) | MEN1KMT2AMITFCA12CA2 | |
| SCHEMBL8343416 | 0.84 | NPC1 (0.59) | MEN1KMT2AMAPK1ALDH1A1TSHR | |
| SCHEMBL3019610 | 0.83 | CACNA1B (0.43) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3019605 | 0.83 | CACNA1B (0.43) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3019608 | 0.83 | CACNA1B (0.43) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL6242641 | 0.82 | MEN1 (0.81) | MEN1KMT2AMITFFFAR1CYP26A1 | |
| SCHEMBL3018673 | 0.80 | NR1H4 (0.60) | MEN1KMT2AFFAR1TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431613-B2 | Memory fixation accelerator | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2013-04-30 | — | — | US | claimed |
| US-20120214763-A1 | MEMORY FIXATION ACCELERATOR | KEMPHYS LTD. (JP) | 2012-08-23 | — | — | US | claimed |
| US-8168677-B2 | Method for treatment of inflammatory bowel disease | KEMPHYS LTD. (JP) | 2012-05-01 | — | — | US | claimed |
| US-20110172184-A1 | ANTITUMOR AGENT CONTAINING 4 - [[3,5 - BIS (TRIMETHYLSILYL) BENZOYL] AMINO] BENZOIC ACID | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2011-07-14 | — | — | US | claimed |
| EP-2324836-A1 | ANTITUMOR AGENT CONTAINING 4-[[3,5-BIS(TRIMETHYLSILYL)BENZOYL]AMINO¨BENZOIC ACID | Taiho Pharmaceutical Co., Ltd. (JP) | 2011-05-25 | — | — | EP | claimed |
| US-20100063162-A1 | METHOD FOR PREDICTING EFFICACY OF RAR-ALPHA AGONIST | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-11 | — | — | US | claimed |
| US-20100004203-A1 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF BOWEL DISEASE | KEMPHYS LTD. (JP) | 2010-01-07 | — | — | US | claimed |
| US-20080275002-A1 | Method for Treatment of Hepatic Cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2008-11-06 | — | — | US | claimed |
| US-20080255069-A1 | Medicament for Preventive and/or Therapeutic Treatment of Bowel Disease | R & R INC. (JP) | 2008-10-16 | — | — | US | claimed |
| EP-1950293-A1 | METHOD FOR PREDICTION OF EFFECTIVENESS OF RAR- AGONIST | Taiho Pharmaceutical Co., Ltd. (JP) | 2008-07-30 | — | — | EP | claimed |
| US-20080021108-A1 | Memory Fixation Accelerator | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2008-01-24 | — | — | US | claimed |
| EP-1862168-A1 | METHOD OF TREATING LIVER CANCER | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-05 | — | — | EP | claimed |
| EP-1733722-A1 | MEMORY FIXATION ACCELERATOR | Research Foundation Itsuu Laboratory (JP) | 2006-12-20 | — | — | EP | claimed |
| US-20050234130-A1 | Medicament for therapeutic treatment of vascular disease | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2005-10-20 | — | — | US | claimed |
| EP-1500401-A1 | DRUGS FOR TREATING VASCULAR DISEASES | Research Foundation Itsuu Laboratory (JP) | 2005-01-26 | — | — | EP | claimed |
| EP-1025857-A1 | RETINOIC ACID AGONISTS AS PREVENTIVE AND THERAPEUTIC AGENTS FOR NEPHRITIS | Eisai Co., Ltd. (JP) | 2000-08-09 | — | — | EP | claimed |
| US-RE36477-E | 4-(3,5-BIS(TRIMETHYLSILYLPHENYL)CARBOXAMIDO)BENZOIC ACID; DIFFERENTIATION-INDUCING REAGENT OR CELLS; ANTICARCINOGENTIC, -TUMOR,-INFLAMMATORY AND -PROLIFERATIVE AGENTS; PSORIASIS; LEUKEMIA; IMMUNOLOGY | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | claimed |
| EP-0337176-B1 | Novel benzoic acid derivatives and process for preparing the same | SHUDO KOICHI (JP) | 1994-12-21 | — | — | EP | claimed |
| US-5155249-A | Differentiating neoplastic cells, treating psoriasis, immune or inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | claimed |
| EP-0337176-A2 | Novel benzoic acid derivatives and process for preparing the same | Shudo, Koichi, Prof. Dr. (JP) | 1989-10-18 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255069-A1 | Medicament for Preventive and/or Therapeutic Treatment of Bowel Disease | FABP2, RARG, RARA | MEN1 3271/4885KMT2A 1642/4885MITF 1915/4885 |
| US-20120214763-A1 | MEMORY FIXATION ACCELERATOR | BDNF, RXRA, RARA | MEN1 3549/4885KMT2A 364/4885MITF 1357/4885 |
| US-20100063162-A1 | METHOD FOR PREDICTING EFFICACY OF RAR-ALPHA AGONIST | RARA, RARB, RARG | MEN1 4026/4885KMT2A 1781/4885MITF 1108/4885 |
| US-20080021108-A1 | Memory Fixation Accelerator | BDNF, RARA, RXRA | MEN1 3414/4885KMT2A 358/4885MITF 1564/4885 |
| US-20080275002-A1 | Method for Treatment of Hepatic Cancer | SLC10A1, SLC10A2, GLS2 | MEN1 674/4885KMT2A 690/4885MITF 4252/4885 |
| US-20100004203-A1 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF BOWEL DISEASE | FABP2, RARG, RARA | MEN1 3271/4885KMT2A 1642/4885MITF 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.