Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710023 | 0.86 | RAB9A (0.76) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL8344728 | 0.85 | HPSE (0.56) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL4608617 | 0.81 | SMN1; SMN2 (0.76) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL23070479 | 0.79 | RAB9A (0.80) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL8343416 | 0.79 | NPC1 (0.59) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL8343312 | 0.79 | TSHR (0.52) | RAB9AKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13066001 | 0.78 | TOP1 (0.46) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL2835923 | 0.78 | PTPN1 (0.81) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL13065753 | 0.78 | FADS1 (0.47) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL677770 | 0.77 | RAB9A (1.00) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36477-E | 4-(3,5-BIS(TRIMETHYLSILYLPHENYL)CARBOXAMIDO)BENZOIC ACID; DIFFERENTIATION-INDUCING REAGENT OR CELLS; ANTICARCINOGENTIC, -TUMOR,-INFLAMMATORY AND -PROLIFERATIVE AGENTS; PSORIASIS; LEUKEMIA; IMMUNOLOGY | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0337176-B1 | Novel benzoic acid derivatives and process for preparing the same | SHUDO KOICHI (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5155249-A | Differentiating neoplastic cells, treating psoriasis, immune or inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| US-5081271-A | Differentiation-inducing agent for neoplastic cells; therapeutic agent for psoriasis or immune and inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0337176-A2 | Novel benzoic acid derivatives and process for preparing the same | Shudo, Koichi, Prof. Dr. (JP) | 1989-10-18 | — | — | EP | disclosed |