SCHEMBL8345240

SCHEMBL8345240

COc1ccc2[nH]c(=O)ccc2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
HCAR1 Q9BXC0 2/20 0.39
BTK Q06187 1/20 0.37
CA1 P00915 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA13 Q8N1Q1 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
PDE3B Q13370 4/20 0.37
PDE3A Q14432 4/20 0.37
F11 P03951 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2E1 P05181 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30564985 1.00 SIRT2 (0.45) SIRT2SIRT1CA12CA9HCAR1
SCHEMBL3862792 0.76 CYP1A2 (0.39) HCAR1PDE3BPDE3ACYP1A2CYP2E1
SCHEMBL4535528 0.76 CA12 (0.48) CA12CA9HCAR1CA1CA3
SCHEMBL586544 0.74 CLK1 (0.49) SIRT2SIRT1CA12CA9BTK
SCHEMBL16751340 0.73 PDE10A (0.46) SIRT2SIRT1PDE3ACYP1A2POLB
SCHEMBL12614229 0.73 SIRT2 (0.46) SIRT2SIRT1CYP1A2CYP2C19ADORA2A
SCHEMBL29377868 0.73 AXL (0.49) SIRT2SIRT1CYP1A2CYP2C19ADORA2A
SCHEMBL9959317 0.73 AXL (0.49) SIRT2SIRT1CYP1A2CYP2C19ADORA2A
SCHEMBL706097 0.72 DDAH1 (0.43) SIRT2SIRT1BTKCYP1A2ADORA2A
SCHEMBL29547698 0.72 CA12 (0.41) CA12CA9HCAR1CA1CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117224450-A Fennel face essence with good moisture retention and preparation method thereof 广州市玑蜜生物科技有限公司 2023-12-15 CN claimed
CN-116687802-A Mouthwash for oral cavity and tooth care and preparation method thereof 广州宏康医药科技有限公司 2023-09-05 CN claimed
US-20250221294-A1 POLYMER, ORGANIC SEMICONDUCTOR MATERIAL, STRETCHABLE POLYMER THIN FILM, AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-07-03 US disclosed
US-12329023-B2 Polymer and stretchable polymer thin film and electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-06-10 US disclosed
US-12239007-B2 Polymer, organic solar cell comprising polymer, perovskite solar cell comprising polymer SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-02-25 US disclosed
US-20240409809-A1 PHOSPHOR MONOMOLECULAR COMPOUND, ORGANIC TRANSISTOR USING SAME, AND WATER DECOMPOSITION AND HYDROGEN PRODUCTION PHOTOCATALYTIC SYSTEM USING SAME SEOUL NAT UNIV R&DB FOUNDATION (KR) 2024-12-12 US disclosed
US-12104104-B2 Phosphor monomolecular compound, organic transistor using same, and water decomposition and hydrogen production photocatalytic system using same SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-10-01 US disclosed
CN-117224450-A Fennel face essence with good moisture retention and preparation method thereof 广州市玑蜜生物科技有限公司 2023-12-15 CN disclosed
CN-116687802-A Mouthwash for oral cavity and tooth care and preparation method thereof 广州宏康医药科技有限公司 2023-09-05 CN disclosed
US-11711965-B2 Polymer, organic solar cell comprising polymer, perovskite solar cell comprising polymer SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-07-25 US disclosed
US-11711965-B2 Polymer, organic solar cell comprising polymer, perovskite solar cell comprising polymer SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-07-25 US disclosed
WO-2019203481-A1 PHOSPHOR MONOMOLECULAR COMPOUND, ORGANIC TRANSISTOR USING SAME, AND WATER DECOMPOSITION AND HYDROGEN PRODUCTION PHOTOCATALYTIC SYSTEM USING SAME 서울대학교 산학협력단 2019-10-24 WO disclosed
US-20190040188-A1 ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2019-02-07 US disclosed
US-20190040188-A1 ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2019-02-07 US disclosed
WO-2017133752-A1 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS MERCK PATENT GMBH (DE) 2017-08-10 WO disclosed
US-20150144846-A1 ORGANIC SEMICONDUCTOR MERCK PATENT GMBH (DE) 2015-05-28 US disclosed
US-20150144846-A1 ORGANIC SEMICONDUCTOR MERCK PATENT GMBH (DE) 2015-05-28 US disclosed
US-20150144846-A1 ORGANIC SEMICONDUCTOR MERCK PATENT GMBH (DE) 2015-05-28 US disclosed
WO-2004014384-A2 CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2004-02-19 WO disclosed
WO-2004014389-A1 3,4-DIHYDROQUINOLIN-2-ONE, 5,6-FUSED OXAZIN-3-ONE, AND 5,6-FUSED THIAZIN-3-ONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190040188-A1 ORGANIC SEMICONDUCTORS OCIAD2, OCIAD1, PPOX SIRT2 2991/4885SIRT1 2405/4885CA12 4644/4885
US-20150144846-A1 ORGANIC SEMICONDUCTOR OCIAD2, OCIAD1, DDT SIRT2 2665/4885SIRT1 2391/4885CA12 4511/4885
US-20240409809-A1 PHOSPHOR MONOMOLECULAR COMPOUND, ORGANIC TRANSISTOR USING SAME, AND WATER DECOMPOSITION AND HYDROGEN PRODUCTION PHOTOCATALYTIC SYSTEM USING SAME INPP5D, INPP5B, PPA1 SIRT2 2934/4885SIRT1 2640/4885CA12 3298/4885
US-12104104-B2 Phosphor monomolecular compound, organic transistor using same, and water decomposition and hydrogen production photocatalytic system using same INPP5D, ATIC, INPP5B SIRT2 2992/4885SIRT1 2764/4885CA12 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.