Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664653 | 0.78 | MMP2 (0.52) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6666012 | 0.78 | MMP2 (0.52) | MEN1KMT2AALDH1A1 | |
| SCHEMBL24440592 | 0.75 | MMP9 (0.47) | PPARAL3MBTL1PPARGMMEALDH1A1 | |
| SCHEMBL5001271 | 0.71 | PPARA (0.67) | PPARACTSSLMNAPPARGALDH1A1 | |
| SCHEMBL5001274 | 0.71 | PPARA (0.67) | PPARACTSSLMNAPPARGALDH1A1 | |
| SCHEMBL20546110 | 0.69 | ATM (0.39) | KDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL19248953 | 0.69 | POLB (0.43) | MEN1KMT2ALMNAMMEALDH1A1 | |
| Hydrochloric Acid SCHEMBL6667478 | 0.68 | SLC1A5 (0.52) | KDM4ETACR1PPARAMAOBPPARG | |
| SCHEMBL6663760 | 0.68 | PPARA (0.44) | FOLH1PPARACTSSLMNAPPARG | |
| SCHEMBL19015871 | 0.67 | CYP1A2 (0.41) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014882-A2 | PROTEASOME INHIBITORS : PEPTIDE DERIVATIVES HAVING C-TERMINAL HETEROARYL GROUPS | AXYS PHARMACEUTICALS (US) | 2004-02-19 | — | — | WO | disclosed |