Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827224 | 0.87 | KDM4E (0.49) | ALDH1A1TSHRKDM4EHSD17B10POLB | |
| SCHEMBL7831629 | 0.83 | GHSR (0.42) | ALDH1A1POLBTP53P2RX7THRB | |
| SCHEMBL8800003 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4EHSD17B10POLB | |
| SCHEMBL7827815 | 0.79 | MEN1 (0.44) | ALDH1A1POLBTP53THRBMAPT | |
| SCHEMBL7815783 | 0.79 | MEN1 (0.44) | ALDH1A1POLBTP53THRBMAPT | |
| SCHEMBL7823515 | 0.78 | TSHR (0.40) | TSHRPOLBRAB9AMAPK8 | |
| SCHEMBL7823417 | 0.78 | MEN1 (0.43) | ALDH1A1POLBTP53THRBMAPT | |
| SCHEMBL8341651 | 0.77 | RAB9A (0.45) | ALDH1A1TSHRKDM4EHSD17B10POLB | |
| SCHEMBL7831438 | 0.77 | AKR1B1 (0.42) | HSD17B10POLBTP53MAPTRAB9A | |
| SCHEMBL7816995 | 0.76 | MEN1 (0.41) | ALDH1A1POLBTP53THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |