Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PARG | Q86W56 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342999 | 0.92 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL7354092 | 0.84 | GRIN1 (0.42) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL8343160 | 0.81 | DAO (0.37) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL7355341 | 0.80 | GRIN2D (0.63) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL8340355 | 0.80 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL8340390 | 0.80 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL8345928 | 0.78 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL8346149 | 0.74 | PGR (0.37) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL8346061 | 0.74 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIN1 | |
| SCHEMBL7353289 | 0.73 | GRIK1 (0.40) | GRIA1GRIA2GRIA3GRIA4GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |