SCHEMBL8346255

SCHEMBL8346255

CCOC(OCCOC)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13618125 0.87 THRB (0.38) LMNATHRB
SCHEMBL17394474 0.84 LMNA (0.36) LMNATHRB
SCHEMBL1250515 0.83 CA2 (0.32)
SCHEMBL4094836 0.82 LMNA (0.53) LMNATHRB
SCHEMBL892322 0.75 LMNA (0.63) LMNATHRB
SCHEMBL8071352 0.74 LMNA (0.71) LMNATHRB
SCHEMBL12065454 0.74
SCHEMBL13618119 0.72 PIK3CD (0.31)
SCHEMBL13618120 0.72
SCHEMBL16919273 0.72 THRB (0.61) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1463502-B1 BROADSPECTRUM HETEROCYCLIC SUBSTITUTED PHENYL CONTAINING SULFONAMIDE HIV PROTEASE INHIBITORS TIBOTEC PHARM LTD (IE) 2011-07-13 EP disclosed
WO-2003053435-A1 BROADSPECTRUM HETEROCYCLIC SUBSTITUTED PHENYL CONTAINING SULFONAMIDE HIV PROTEASE INHIBITORS TIBOTEC PHARMACEUTICALS LTD (IE) 2003-07-03 WO disclosed