Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346256 | 0.91 | TDP1 (0.44) | TDP1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL7620864 | 0.77 | SMN1; SMN2 (0.44) | TDP1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL581884 | 0.76 | PPARA (0.59) | TDP1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL11369656 | 0.75 | SMN1; SMN2 (0.42) | TDP1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL581322 | 0.73 | TSHR (0.64) | TDP1TSHRCYP1A2SMN1; SMN2HPGD | |
| SCHEMBL11450125 | 0.73 | TDP1 (0.60) | TDP1TSHRCYP2C19SMN1; SMN2HPGD | |
| SCHEMBL10390782 | 0.71 | LMNA (0.52) | TDP1TSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL9573108 | 0.71 | TDP1 (0.66) | TDP1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL13876906 | 0.70 | SLC6A2 (0.48) | TDP1TSHRHPGDL3MBTL1MAPT | |
| SCHEMBL30490487 | 0.69 | TDP1 (0.50) | TDP1TSHRCYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012899-A1 | A PROCESS FOR MAKING PROSTAGLANDIN F ANALOGS | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-18 | — | — | WO | disclosed |