Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620864 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDTSHRNPC1RAB9A | |
| SCHEMBL7616018 | 0.81 | PPARA (0.55) | SMN1; SMN2HPGDTSHRMAPTTDP1 | |
| SCHEMBL15438107 | 0.78 | MAPT (0.49) | SMN1; SMN2HPGDTSHRMAPTTDP1 | |
| SCHEMBL11516039 | 0.77 | PPARA (0.51) | SMN1; SMN2HPGDTSHRMAPTTDP1 | |
| SCHEMBL581884 | 0.75 | PPARA (0.59) | SMN1; SMN2HPGDTSHRNPC1RAB9A | |
| SCHEMBL8346258 | 0.75 | TDP1 (0.46) | SMN1; SMN2HPGDTSHRNPC1RAB9A | |
| SCHEMBL8346256 | 0.74 | TDP1 (0.44) | SMN1; SMN2HPGDTSHRNPC1RAB9A | |
| SCHEMBL581322 | 0.72 | TSHR (0.64) | SMN1; SMN2HPGDTSHRNPC1RAB9A | |
| SCHEMBL2322156 | 0.72 | ALDH1A1 (0.56) | SMN1; SMN2HPGDTSHRNPC1RAB9A | |
| SCHEMBL9255616 | 0.72 | PPARG (0.43) | MAPTLMNAKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304907-A | Bicyclo lactone intermediates for prostaglandin analogs | THE UPJOHN COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| US-4303796-A | 16-Phenoxy prostaglandin F2α analogs | THE UPJOHN COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| US-4116988-A | 16-Phenoxy prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4116989-A | 16-Phenoxy prostaglandin F1α analogs | THE UPJOHN COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4087616-A | 16-Phenoxy prostaglandin A2 analogs | THE UPJOHN COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |