Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350558 | 0.83 | AGTR1 (0.48) | AGTR2AGTR1 | |
| SCHEMBL28421136 | 0.81 | AGTR1 (0.62) | AGTR2AGTR1 | |
| SCHEMBL7305298 | 0.75 | AGTR1 (0.58) | AGTR2AGTR1 | |
| SCHEMBL29833188 | 0.74 | PPARG (0.70) | — | |
| SCHEMBL29833187 | 0.74 | PPARG (0.70) | — | |
| SCHEMBL8565506 | 0.74 | AGTR2 (0.69) | AGTR2AGTR1 | |
| SCHEMBL8823608 | 0.73 | AGTR1 (0.59) | AGTR2AGTR1 | |
| SCHEMBL7310565 | 0.73 | AGTR1 (0.59) | AGTR2AGTR1 | |
| SCHEMBL7310582 | 0.73 | AGTR2 (0.49) | AGTR2AGTR1 | |
| SCHEMBL9424026 | 0.72 | PDE4A (0.46) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005105-A | Process for producing imidazole derivative | PHARMACIA & UPJOHN COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0705266-B1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVE | UPJOHN CO (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0705266-A1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVE | UPJOHN CO (US) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000517-A1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVE | THE UPJOHN COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |