Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109902 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2TLR7 | |
| SCHEMBL8346282 | 0.83 | AGTR2 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9471931 | 0.81 | PTGS2 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9879808 | 0.80 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL7308185 | 0.77 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8564634 | 0.76 | AGTR2 (0.57) | AGTR1AGTR2 | |
| SCHEMBL870 | 0.75 | PPARG (0.57) | — | |
| SCHEMBL1256306 | 0.74 | TLR7 (0.56) | AGTR1AGTR2TLR7TLR8 | |
| SCHEMBL15331639 | 0.74 | TLR7 (0.54) | AGTR1AGTR2TLR7TLR8 | |
| SCHEMBL7306374 | 0.73 | AGTR1 (0.49) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005105-A | Process for producing imidazole derivative | PHARMACIA & UPJOHN COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0705266-B1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVE | UPJOHN CO (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0705266-A1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVE | UPJOHN CO (US) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000517-A1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVE | THE UPJOHN COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |