Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564634 | 0.89 | AGTR2 (0.57) | AGTR2AGTR1 | |
| SCHEMBL708 | 0.89 | AGTR1 (0.80) | AGTR2AGTR1 | |
| SCHEMBL9468705 | 0.88 | AGTR1 (0.78) | AGTR2AGTR1 | |
| SCHEMBL9483479 | 0.84 | AGTR2 (0.76) | AGTR2AGTR1 | |
| SCHEMBL29308427 | 0.84 | AGTR2 (0.65) | AGTR2AGTR1 | |
| SCHEMBL8565334 | 0.84 | AGTR1 (0.73) | AGTR2AGTR1 | |
| SCHEMBL8564639 | 0.84 | AGTR2 (0.67) | AGTR2AGTR1 | |
| SCHEMBL21083640 | 0.83 | AGTR2 (0.66) | AGTR2AGTR1 | |
| SCHEMBL29726833 | 0.83 | AGTR2 (0.66) | AGTR2AGTR1 | |
| SCHEMBL29308428 | 0.83 | AGTR2 (0.64) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649424-B1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | KNOLL AG (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5627191-A | Therapeutic agents | THE BOOTS COMPANY PLC (GB) | 1997-05-06 | — | — | US | disclosed |
| EP-0649424-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | Knoll AG (DE) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001436-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | THE BOOTS COMPANY PLC (GB) | 1994-01-20 | — | — | WO | disclosed |