Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838200 | 0.93 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL11111056 | 0.89 | ALDH1A1 (0.80) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL10802880 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL10993278 | 0.86 | KMT2A (0.71) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL9570672 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL9570550 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL1133893 | 0.84 | KMT2A (0.74) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL29730681 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL3223930 | 0.84 | LMNA (0.74) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL92223 | 0.84 | ALDH1A1 (0.78) | ALDH1A1KMT2AMEN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
| US-5948775-A | OSTEOPOROSIS; ANTICANCER AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-07 | — | — | US | disclosed |
| EP-0355492-B1 | REACTIVE DYES | BAYER AG (DE) | 1992-12-09 | — | — | EP | disclosed |
| US-5138054-A | Colorfastness, photostability; red dye | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0355492-A1 | Reactive dyes | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4137328-A | CONGESTIVE HEART FAILURE | PFIZER INC. (US) | 1979-01-30 | — | — | US | disclosed |