SCHEMBL8347012

SCHEMBL8347012

Cc1cc(Cc2c(C)c(C)c(O)c(Cc3cc(C)c(O)c(CO)c3C)c2C)c(C)c(CO)c1O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.40
TP53 P04637 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SIRT1 Q96EB6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7529731 0.90 SHBG (0.44) SHBGTP53CYP2C9CYP2C19SMN1; SMN2
SCHEMBL7523362 0.90 SHBG (0.44) SHBGTP53CYP2C9CYP2C19SMN1; SMN2
SCHEMBL212514 0.86 SHBG (0.47) SHBGTP53CYP2C9CYP2C19SMN1; SMN2
SCHEMBL22271434 0.84 SHBG (0.43) SHBGCYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL8351608 0.83 SHBG (0.40) SHBGCYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL209920 0.81 SHBG (0.41) SHBGKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8755476 0.80 AMY1A (0.51) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL7522113 0.80 SHBG (0.48) SHBGKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8345472 0.79 SHBG (0.42) SHBGCYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL7524172 0.79 AMY1A (0.44) SHBGTP53CYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866724-A Positive resist composition and photosensitizers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed
EP-0769485-A1 Positive resist composition and photosensitizers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-04-23 EP disclosed