Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380313 | 0.82 | HPGD (0.65) | KMT2AGAAMEN1HPGDLMNA | |
| SCHEMBL4774542 | 0.81 | HTT (0.44) | KMT2AGAAMEN1HPGDLMNA | |
| SCHEMBL214224 | 0.78 | GAA (0.49) | KMT2AGAAMEN1HPGDLMNA | |
| SCHEMBL4774535 | 0.74 | ALDH1A1 (0.43) | KMT2AGAAMEN1HPGDALDH1A1 | |
| SCHEMBL10271853 | 0.74 | GAA (0.70) | KMT2AGAAMEN1HPGDLMNA | |
| SCHEMBL8347159 | 0.72 | ALDH1A1 (0.49) | KMT2AGAAMEN1HPGDLMNA | |
| SCHEMBL6445364 | 0.72 | ADORA1 (0.65) | KMT2AMEN1HPGDLMNAALDH1A1 | |
| SCHEMBL213872 | 0.71 | GAA (0.57) | KMT2AGAAMEN1HPGDLMNA | |
| SCHEMBL10466353 | 0.70 | GAA (1.00) | KMT2AGAAMEN1HPGDLMNA | |
| SCHEMBL6440793 | 0.70 | XDH (0.66) | KMT2AGAAMEN1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024159-A1 | INHIBITORS OF TFGβ | SCIOS INC. (US) | 2004-03-25 | — | — | WO | disclosed |