Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 16/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350410 | 0.89 | KMT2A (0.38) | KMT2A | |
| SCHEMBL8356065 | 0.87 | KMT2A (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8355974 | 0.87 | CA12 (0.42) | CYP2C9CYP3A4CYP2C19CYP2D6KMT2A | |
| SCHEMBL8347396 | 0.87 | TACR2 (0.48) | CYP2C9CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL8349962 | 0.85 | TACR2 (0.50) | TSHRALDH1A1 | |
| SCHEMBL8347206 | 0.84 | TACR2 (0.51) | — | |
| SCHEMBL8348494 | 0.84 | TACR2 (0.50) | USP2TSHRHIF1ACYP3A4CYP1A2 | |
| SCHEMBL8351517 | 0.83 | SMN1; SMN2 (0.45) | TSHRKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8636699 | 0.83 | SPR (0.40) | KMT2A | |
| SCHEMBL8355522 | 0.81 | TACR2 (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861416-A | TREATMENT OF ASTHMA OR COUGH | MERRELL PHARMACEUTICALS INC. (US) | 1999-01-19 | — | — | US | disclosed |
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |