Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 6/20 | 0.40 |
| ▸ | TACR1 | P25103 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355501 | 0.90 | TACR2 (0.51) | TACR2TACR1KMT2A | |
| SCHEMBL8347396 | 0.88 | TACR2 (0.48) | TACR2TACR1 | |
| SCHEMBL8355974 | 0.86 | CA12 (0.42) | TACR2TACR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8350410 | 0.85 | KMT2A (0.38) | TACR2TACR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8355522 | 0.85 | TACR2 (0.53) | TACR2TACR1 | |
| SCHEMBL8355997 | 0.84 | CCR4 (0.41) | TACR2TACR1SLC6A9 | |
| SCHEMBL8350132 | 0.83 | TACR2 (0.53) | TACR2TACR1NPC1 | |
| SCHEMBL8356065 | 0.83 | KMT2A (0.39) | TACR2TACR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8349962 | 0.83 | TACR2 (0.50) | TACR2TACR1 | |
| SCHEMBL8348494 | 0.83 | TACR2 (0.50) | TACR2TACR1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |