Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 5/20 | 0.44 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.43 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224003 | 0.83 | PIK3R2 (0.39) | NCF1PIK3R2MEN1KMT2ARORC | |
| SCHEMBL4243255 | 0.81 | NR4A2 (0.61) | NCF1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL13855104 | 0.81 | SLC9A1 (0.50) | NCF1SLC9A1SLC9A2MEN1KMT2A | |
| SCHEMBL4240199 | 0.81 | L3MBTL1 (0.43) | NCF1PIK3R2MEN1KMT2ARORC | |
| SCHEMBL8346357 | 0.80 | SLC9A1 (0.42) | SLC9A1SLC9A2RORC | |
| SCHEMBL8349128 | 0.77 | SLC9A1 (0.49) | SLC9A1SLC9A2MEN1KMT2A | |
| SCHEMBL8337393 | 0.76 | NCF1 (0.45) | NCF1PIK3R2SLC9A1MEN1KMT2A | |
| SCHEMBL8347963 | 0.76 | SLC9A1 (0.42) | SLC9A1SLC9A2 | |
| Trifluoroacetic Acid SCHEMBL4243180 | 0.76 | PIK3R2 (0.41) | NCF1PIK3R2MEN1KMT2ARORC | |
| SCHEMBL13855106 | 0.76 | SLC9A1 (0.43) | SLC9A1SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638521-B2 | 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, preparation process, their use as medicaments, and pharmaceutical compositions comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| US-7638521-B2 | 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, preparation process, their use as medicaments, and pharmaceutical compositions comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| WO-2004007479-A1 | 3-GUANIDINOCARBONYL-1-HETEROARYL-INDOLE DERIVATIVES, PREPARATION PROCESS, THEIR USE AS MEDICAMENTS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-01-22 | — | — | WO | disclosed |