Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13074384 | 0.90 | MAPT (0.54) | HDAC1MAPTTP53MEN1KMT2A | |
| SCHEMBL12933415 | 0.86 | MAPT (0.51) | HDAC1MAPTTP53MEN1KMT2A | |
| SCHEMBL8348225 | 0.80 | DYRK1A (0.67) | HDAC1MAPTTP53SMN1; SMN2AGTR1 | |
| SCHEMBL2175274 | 0.78 | MEN1 (0.72) | MAPTTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10686590 | 0.77 | MEN1 (0.57) | MAPTTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4502579 | 0.77 | KDM4E (0.68) | MAPTTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6749872 | 0.76 | HSP90AA1 (0.61) | MAPTMEN1KMT2ASMN1; SMN2AGTR1 | |
| SCHEMBL4489879 | 0.73 | MEN1 (0.54) | MAPTTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7834331 | 0.72 | LMNA (0.60) | MAPTMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8345562 | 0.71 | LMNA (0.47) | MAPTKMT2AL3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069823-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2004-08-19 | — | — | WO | disclosed |
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |