Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 16/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | KDM6A | O15550 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327558 | 1.00 | KDM4D (0.45) | KDM4DCTSKKDM6AJAK2JAK1 | |
| SCHEMBL6400934 | 0.91 | KDM4D (0.47) | KDM4DCTSKKDM6A | |
| SCHEMBL6325415 | 0.91 | KDM4D (0.47) | KDM4DCTSKKDM6A | |
| SCHEMBL8349034 | 0.83 | CTSL (0.49) | CTSK | |
| SCHEMBL8363823 | 0.83 | KDM4D (0.43) | KDM4DKDM6A | |
| SCHEMBL14375271 | 0.79 | GAA (0.38) | — | |
| SCHEMBL8366352 | 0.78 | SIRT2 (0.46) | KDM4D | |
| SCHEMBL8348613 | 0.78 | SIRT2 (0.46) | KDM4D | |
| Trifluoroacetic Acid SCHEMBL6327175 | 0.77 | CPB2 (0.43) | — | |
| SCHEMBL6326900 | 0.76 | CTSL (0.51) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003061653-A9 | 3-(IMIDAZOLYL)-2-AMINOPROPANOIC ACIDS FOR USE AS TAFI-A INHIBITORS FOR THE TREATMENT OF THROMBOTIC DISEASES | PFIZER LTD (GB) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003061653-A1 | 3-(IMIDAZOLYL)-2-AMINOPROPANOIC ACIDS FOR USE AS TAFI-A INHIBITORS FOR THE TREATMENT OF THROMBOTIC DISEASES | PFIZER LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |