Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 17/20 | 0.47 |
| ▸ | KDM6A | O15550 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325415 | 1.00 | KDM4D (0.47) | KDM4DKDM6ACTSKCCR5 | |
| SCHEMBL6327558 | 0.91 | KDM4D (0.45) | KDM4DKDM6ACTSK | |
| SCHEMBL8348986 | 0.91 | KDM4D (0.45) | KDM4DKDM6ACTSK | |
| SCHEMBL6333894 | 0.82 | KDM4D (0.46) | KDM4DKDM6A | |
| SCHEMBL6326900 | 0.82 | CTSL (0.51) | CTSK | |
| SCHEMBL8366110 | 0.79 | CTSK (0.52) | KDM4DKDM6ACTSK | |
| SCHEMBL6335174 | 0.78 | KCNA3 (0.43) | KDM4D | |
| SCHEMBL6326986 | 0.78 | KCNA3 (0.43) | KDM4D | |
| SCHEMBL6335407 | 0.78 | KCNA3 (0.43) | KDM4D | |
| SCHEMBL8349034 | 0.77 | CTSL (0.49) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919457-B2 | 3-(imidazolyl)-2-aminopropanoic acids | PFIZER, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20050137416-A1 | Process and intermediates for preparing a cyclohexylnitrile | SMITHKLINE BEECHAM CORPORATION | 2005-06-23 | — | — | US | disclosed |
| US-20040192668-A1 | 3-(imidazolyl)-2-aminopropanoic acids | PFIZER INC | 2004-09-30 | — | — | US | disclosed |
| US-6759426-B2 | RESPIRATORY SYSTREM DISORDERS; ANTIINFLAMMATORY AGENTS; RHEUMATIC DISORDERS | PFIZER INC | 2004-07-06 | — | — | US | disclosed |
| US-20030191107-A1 | 3-(Imidazolyl)-2-aminopropanoic acids | PFIZER INC. | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137416-A1 | Process and intermediates for preparing a cyclohexylnitrile | HPD, PCCA, MCCC2 | KDM4D 1606/4885KDM6A 1289/4885CTSK 688/4885 |
| US-20040192668-A1 | 3-(imidazolyl)-2-aminopropanoic acids | FGB, F2, F11 | KDM4D 3673/4885KDM6A 2138/4885CTSK 3370/4885 |
| US-20030191107-A1 | 3-(Imidazolyl)-2-aminopropanoic acids | FGB, F2, F11 | KDM4D 3673/4885KDM6A 2138/4885CTSK 3370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.