Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GNG2 | P59768 | 1/20 | 0.48 |
| ▸ | GNB1 | P62873 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094062 | 0.84 | DHFR (0.53) | DHFR | |
| SCHEMBL28854429 | 0.76 | GNG2 (0.81) | MEN1MMP1MMP9ALOX15BLM | |
| SCHEMBL4357022 | 0.76 | MAP4K4 (0.54) | DHFRMEN1KMT2A | |
| SCHEMBL8222070 | 0.76 | DHFR (0.57) | DHFR | |
| SCHEMBL10479133 | 0.75 | MAOB (0.53) | MEN1KMT2A | |
| SCHEMBL6095892 | 0.75 | ULK1 (0.61) | DHFR | |
| SCHEMBL29010947 | 0.74 | DHFR (0.59) | DHFR | |
| SCHEMBL6004946 | 0.74 | DHFR (0.69) | DHFR | |
| SCHEMBL30795245 | 0.74 | DHFR (0.69) | DHFR | |
| SCHEMBL4753528 | 0.73 | TDP1 (0.51) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999025327-A2 | SMALL MOLECULE INTERVENTION IN HIV-1 REPLICATION | WARNER-LAMBERT COMPANY (US) | 1999-05-27 | — | — | WO | claimed |
| WO-1999025327-A2 | SMALL MOLECULE INTERVENTION IN HIV-1 REPLICATION | WARNER-LAMBERT COMPANY (US) | 1999-05-27 | — | — | WO | disclosed |