Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA6 | P23280 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
| ▸ | TUBB | P07437 | 1/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243460 | 0.98 | CALM1 (0.72) | CALM1ALOX15ALOX12CA2CA1 | |
| SCHEMBL68178 | 0.92 | CALM1 (0.79) | CALM1ALOX15ALOX12CA2TAAR1 | |
| SCHEMBL21357334 | 0.89 | CALM1 (0.70) | CALM1ALOX15ALOX12CA2TAAR1 | |
| SCHEMBL15042812 | 0.89 | TUBB4A (0.75) | CALM1ALOX15ALOX12CA2TAAR1 | |
| SCHEMBL29442255 | 0.89 | TUBB4A (0.75) | CALM1ALOX15ALOX12CA2TAAR1 | |
| SCHEMBL28795975 | 0.87 | CALM1 (0.68) | CALM1CA2TAAR1TSHRMAPK1 | |
| SCHEMBL27758491 | 0.86 | CALM1 (0.66) | CALM1CA2TAAR1TSHRMAPK1 | |
| SCHEMBL10683411 | 0.84 | ALOX15 (0.70) | CALM1ALOX15ALOX12AKR1B1TAAR1 | |
| SCHEMBL27779669 | 0.83 | CALM1 (0.62) | CALM1CA2TAAR1TSHRMAPK1 | |
| Dopamine SCHEMBL27902229 | 0.82 | TAAR1 (0.90) | ALOX15ALOX12AKR1B1TAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101927-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES SUCH AS ALZHEIMER'S DISEASE, TYPE 2 DIABETES, AND PARKINSON'S DISEASE | PROTEOTECH, INC. (US) | 2003-12-11 | — | — | WO | disclosed |