Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511158 | 1.00 | CASP3 (0.52) | CASP3MDM2IDO1KMT2AMDM4 | |
| SCHEMBL13163967 | 0.91 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL29361981 | 0.91 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL29386346 | 0.91 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL7423417 | 0.91 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL29423514 | 0.91 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL2313063 | 0.91 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL7326541 | 0.89 | KMT2A (0.49) | CASP3MDM2IDO1KMT2AMDM4 | |
| SCHEMBL28624889 | 0.89 | KMT2A (0.49) | CASP3MDM2IDO1KMT2AMDM4 | |
| SCHEMBL28627067 | 0.89 | KMT2A (0.49) | CASP3MDM2IDO1KMT2AMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008058-A | SYNTHESIZING AND SCREENING CYCLIC PEPTIDE LIBRARIES | UNIVERSITY OF LOUISVILLE (US) | 1999-12-28 | — | — | US | disclosed |