SCHEMBL29511158

SCHEMBL29511158

CC(C)(C)OC(=O)N[C@@H](CC(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 3/20 0.52
▸ MDM2 Q00987 1/20 0.49
▸ IDO1 P14902 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ MDM4 O15151 2/20 0.46
▸ TP53 P04637 2/20 0.46
▸ CACNA1B Q00975 1/20 0.46
▸ TLR2 O60603 1/20 0.45
▸ TLR1 Q15399 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8350965 1.00 CASP3 (0.52) CASP3MDM2IDO1KMT2AMDM4
SCHEMBL13163967 0.91 CASP3 (0.57) CASP3MDM2KMT2AMDM4TP53
SCHEMBL29361981 0.91 CASP3 (0.57) CASP3MDM2KMT2AMDM4TP53
SCHEMBL29386346 0.91 CASP3 (0.57) CASP3MDM2KMT2AMDM4TP53
SCHEMBL7423417 0.91 CASP3 (0.57) CASP3MDM2KMT2AMDM4TP53
SCHEMBL29423514 0.91 CASP3 (0.57) CASP3MDM2KMT2AMDM4TP53
SCHEMBL2313063 0.91 CASP3 (0.57) CASP3MDM2KMT2AMDM4TP53
SCHEMBL7326541 0.89 KMT2A (0.49) CASP3MDM2IDO1KMT2AMDM4
SCHEMBL28624889 0.89 KMT2A (0.49) CASP3MDM2IDO1KMT2AMDM4
SCHEMBL28627067 0.89 KMT2A (0.49) CASP3MDM2IDO1KMT2AMDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US disclosed
CN-119119190-A Melanocortin receptor ligands 益普生制药股份有限公司 2024-12-13 — — CN disclosed
CN-105837661-B Melanocortin receptor ligands 益普生制药股份有限公司 2024-10-15 — — CN disclosed
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R CASP3 4594/4885MDM2 3806/4885IDO1 269/4885
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS MC3R, MC1R, MC5R CASP3 3742/4885MDM2 3975/4885IDO1 1309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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