Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350979 | 0.83 | MEN1 (0.44) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL6093649 | 0.67 | KDM4E (0.80) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2984842 | 0.65 | CNOT7 (0.54) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL2993196 | 0.64 | CNOT7 (0.53) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL4161269 | 0.64 | BPTF (0.52) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20611300 | 0.62 | CA12 (0.45) | LMNAMEN1KMT2AMAPTCA12 | |
| SCHEMBL14441697 | 0.62 | ALDH1A1 (0.57) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4612507 | 0.61 | RAB9A (0.57) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL20105594 | 0.61 | KDM4E (0.64) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL22111515 | 0.61 | KDM4E (0.78) | LMNAMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101992-A1 | PROCESS FOR PREPARING XANTHINE PHOSPHODIESTERASE V INHIBITORS AND PRECURSORS THEREOF | SCHERING CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |