Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350976 | 0.83 | LMNA (0.42) | MEN1KMT2ALMNATP53ALDH1A1 | |
| SCHEMBL7434388 | 0.74 | KDM4E (0.67) | MEN1KMT2AALDH1A1GLAGAA | |
| SCHEMBL6093649 | 0.73 | KDM4E (0.80) | MEN1KMT2ALMNAALDH1A1GLA | |
| SCHEMBL4406872 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2ATP53ALDH1A1GLA | |
| SCHEMBL16028787 | 0.69 | ALDH1A1 (0.43) | MEN1KMT2ALMNAALDH1A1GLA | |
| SCHEMBL24304750 | 0.68 | PKM (0.44) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL22111515 | 0.68 | KDM4E (0.78) | MEN1KMT2ALMNAALDH1A1GLA | |
| SCHEMBL20105594 | 0.68 | KDM4E (0.64) | MEN1KMT2ALMNAALDH1A1GLA | |
| SCHEMBL2984842 | 0.67 | CNOT7 (0.54) | MEN1KMT2ALMNATP53ALDH1A1 | |
| SCHEMBL16298385 | 0.66 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101992-A1 | PROCESS FOR PREPARING XANTHINE PHOSPHODIESTERASE V INHIBITORS AND PRECURSORS THEREOF | SCHERING CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |