Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353149 | 0.83 | AGTR1 (0.43) | AGTR2AGTR1 | |
| SCHEMBL8353001 | 0.74 | OPRM1 (0.35) | OPRM1OPRK1AGTR2AGTR1 | |
| SCHEMBL8346738 | 0.72 | AGTR1 (0.42) | AGTR2AGTR1 | |
| SCHEMBL8353003 | 0.71 | AGTR1 (0.53) | AGTR2AGTR1 | |
| SCHEMBL8347253 | 0.71 | AGTR2 (0.48) | AGTR2AGTR1 | |
| SCHEMBL7567015 | 0.70 | LMNA (0.39) | OPRM1OPRK1 | |
| SCHEMBL7567012 | 0.70 | LMNA (0.39) | OPRM1OPRK1 | |
| SCHEMBL6066478 | 0.70 | LMNA (0.39) | OPRM1OPRK1 | |
| SCHEMBL6066487 | 0.70 | LMNA (0.39) | OPRM1OPRK1 | |
| SCHEMBL654704 | 0.70 | LMNA (0.39) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977155-A | CARDIOVASCULAR, KIDNEYS | HOECHST MARION ROUSSEL (FR) | 1999-11-02 | — | — | US | disclosed |