Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12705713 | 0.95 | CYP1A2 (0.58) | GAACYP1A2LMNATHRBBLM | |
| SCHEMBL12705721 | 0.86 | GAA (0.49) | GAACYP1A2LMNATHRBBLM | |
| SCHEMBL36741 | 0.76 | MAPT (0.58) | GAALMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1033226 | 0.76 | CYP1A2 (0.53) | GAACYP1A2LMNATHRBBLM | |
| SCHEMBL3868148 | 0.74 | CYP1A2 (0.50) | GAACYP1A2LMNATHRBBLM | |
| Altretamine SCHEMBL4448907 | 0.70 | LMNA (0.61) | GAACYP1A2LMNATHRBBLM | |
| Pentamethyl Melamine SCHEMBL38832 | 0.70 | LMNA (0.61) | GAACYP1A2LMNATHRBBLM | |
| SCHEMBL15836256 | 0.70 | GAA (0.47) | GAACYP1A2LMNATHRBBLM | |
| SCHEMBL11688741 | 0.70 | MAPT (0.46) | GAACYP1A2LMNACREBBPSMN1; SMN2 | |
| SCHEMBL10724236 | 0.70 | ALDH1A1 (0.56) | GAACYP1A2LMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5904738-A | Gas-fade inhibition | CROMPTON & KNOWLES CORPORATION (US) | 1999-05-18 | — | — | US | disclosed |
| US-4104258-A | DIMENSIONAL AND THERMAL STABILITY, METALLIZATION | AKZONA INCORPORATED (US) | 1978-08-01 | — | — | US | disclosed |
| US-3988292-A | A TRIAZINE DERIVATIVE | TEIJIN LIMITED (JA) | 1976-10-26 | — | — | US | disclosed |