SCHEMBL3868148

SCHEMBL3868148

CN(C)c1nc(NO)nc(NO)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
LMNA P02545 2/20 0.50
POLB P06746 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
CREBBP Q92793 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH1A1 P00352 7/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 4/20 0.38
IDH2 P48735 1/20 0.36
HTT P42858 1/20 0.36
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
ALOX12 P18054 1/20 0.35
PDE4A P27815 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18737196 0.91 PDE4A (0.45) CYP1A2LMNAPOLBTHRBBLM
SCHEMBL27414662 0.82 GAA (0.34) CYP1A2POLBALDH1A1L3MBTL1KDM4E
SCHEMBL1033226 0.76 CYP1A2 (0.53) CYP1A2LMNAPOLBTHRBBLM
SCHEMBL8353255 0.74 GAA (0.59) CYP1A2LMNAPOLBTHRBBLM
SCHEMBL3822649 0.72 KDM4E (0.37) CYP1A2L3MBTL1KDM4ESMN1; SMN2GAA
Altretamine SCHEMBL4448907 0.70 LMNA (0.61) CYP1A2LMNAPOLBTHRBBLM
SCHEMBL1817811 0.70 GAA (0.50) CYP1A2LMNAPOLBTHRBBLM
SCHEMBL10724236 0.70 ALDH1A1 (0.56) CYP1A2LMNAPOLBTHRBBLM
Altretamine SCHEMBL2354769 0.69 LMNA (1.00) CYP1A2LMNAPOLBTHRBBLM
Altretamine SCHEMBL4206 0.69 LMNA (1.00) CYP1A2LMNAPOLBTHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107652570-A A kind of preparation technology of ceramic drying plant resistant material 安徽省德邦瓷业有限公司 2018-02-02 CN claimed
CN-104312407-B A kind of preparation method of aqueous polyurethane coating 宁夏中科天际防雷股份有限公司 2016-08-24 CN claimed
CN-104327710-B The preparation method of the simple coating of a kind of preparation technology QIU GUOFEI (CN) 2016-05-25 CN claimed
CN-107652570-A A kind of preparation technology of ceramic drying plant resistant material 安徽省德邦瓷业有限公司 2018-02-02 CN disclosed
CN-107540967-A Multifunctional leisure seat 安徽新华学院 2018-01-05 CN disclosed
CN-107418081-A Ceramic drying support resistant material 安徽省德邦瓷业有限公司 2017-12-01 CN disclosed
US-9618788-B2 Optical film, polarizing plate and liquid crystal display using the same FUJIFILM CORPORATION (JP) 2017-04-11 US disclosed
CN-104312407-B A kind of preparation method of aqueous polyurethane coating 宁夏中科天际防雷股份有限公司 2016-08-24 CN disclosed
CN-104277193-B The preparation method of polyurethane coating 宁夏中科天际防雷股份有限公司 2016-08-24 CN disclosed
CN-104327710-B The preparation method of the simple coating of a kind of preparation technology QIU GUOFEI (CN) 2016-05-25 CN disclosed
EP-1197799-B1 Silver halide photographic light-sensitive material comprising a yellow dye-forming coupler, and method for producing a yellow azomethine dye FUJIFILM CORP (JP) 2009-11-11 EP disclosed
US-20050020821-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2005-01-27 US disclosed
US-6803181-B2 USING A 1,3-DIKETOOXAZOLIDINE FUJI PHOTO FILM CO., LTD. (JP) 2004-10-12 US disclosed
US-6677110-B2 A DYE HAVING AN EXCELLENT HUE, STORAGE STABILITY, COLORFASTNESS, SHARPNESS AND LOW COST PRODUCTION DUE TO REDUCED STEPS FUJI PHOTO FILM CO., LTD. (JP) 2004-01-13 US disclosed
US-20030229230-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2003-12-11 US disclosed
US-20030064332-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound FUJIFILM CORPORATION (JP) 2003-04-03 US disclosed
US-20020064736-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2002-05-30 US disclosed
EP-1197799-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye Fuji Photo Film Co., Ltd. (JP) 2002-04-17 EP disclosed
EP-0921432-A1 Silver halide light-sensitive photographic comprising a phosphazene compound KONICA CORPORATION (JP) 1999-06-09 EP disclosed
US-4874687-A EXPOSE OF MIXTURE OF SILVER HALIDE EMULSION, HARDENER AND METALLIC SALT; DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 1989-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020064736-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye CBR1, IK, CBR3 CYP1A2 170/4885LMNA 1985/4885POLB 3589/4885
US-20030229230-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye CBR1, IK, CBR3 CYP1A2 170/4885LMNA 1985/4885POLB 3589/4885
US-20030064332-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound CBR1, QDPR, IK CYP1A2 769/4885LMNA 1624/4885POLB 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.