Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352059 | 0.83 | MAPT (0.37) | KDM4EALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL8355025 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10SMN1; SMN2CDK1 | |
| SCHEMBL8354895 | 0.80 | CA2 (0.41) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL7824006 | 0.74 | KMT2A (0.44) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL8358621 | 0.73 | CA2 (0.39) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL3215571 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL7414215 | 0.70 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL3220624 | 0.70 | SMN1; SMN2 (0.57) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL21184279 | 0.70 | LMNA (0.46) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL8356473 | 0.69 | MAPT (0.38) | KDM4EALDH1A1HSD17B10SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001881-A | Ortho-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-14 | — | — | US | disclosed |