Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 5/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.52 |
| ▸ | TTR | P02766 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068874 | 0.84 | PLK1 (0.67) | ABCG2ESR1ESR2CYP3A4CYP19A1 | |
| SCHEMBL27860085 | 0.79 | CYP19A1 (0.51) | ABCG2ESR1ESR2TTRCYP3A4 | |
| SCHEMBL15544304 | 0.77 | MAPT (0.55) | ESR1ESR2TTRCYP3A4CYP19A1 | |
| SCHEMBL476381 | 0.77 | ESR1 (0.75) | ABCG2ESR1ESR2TTRCYP3A4 | |
| SCHEMBL4758120 | 0.77 | ESR1 (0.75) | ABCG2ESR1ESR2TTRCYP3A4 | |
| SCHEMBL30689832 | 0.76 | TTR (0.81) | ESR1ESR2TTRCYP3A4CYP19A1 | |
| SCHEMBL28616923 | 0.76 | TTR (0.81) | ESR1ESR2TTRCYP3A4CYP19A1 | |
| SCHEMBL22422611 | 0.75 | ESR1 (0.73) | ABCG2ESR1ESR2TTRCYP19A1 | |
| SCHEMBL22422612 | 0.74 | ESR1 (0.56) | ABCG2ESR1ESR2TTRCYP19A1 | |
| SCHEMBL15544299 | 0.73 | TTR (0.78) | ESR1ESR2TTRCYP3A4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11106336-A | — | — | None | — | — | JP | disclosed |
| JP-H11106336-A | MAILLARD REACTION INHIBITOR | ICHIMARU PHARCOS CO LTD | 1999-04-20 | — | — | JP | disclosed |