Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358915 | 0.94 | HSD11B1 (0.40) | HSD11B1TSHRALDH1A1L3MBTL1HTR6 | |
| SCHEMBL9831903 | 0.88 | TSHR (0.37) | HSD11B1TSHRALDH1A1L3MBTL1HTR6 | |
| SCHEMBL8358876 | 0.88 | TSHR (0.37) | HSD11B1TSHRALDH1A1L3MBTL1HTR6 | |
| SCHEMBL9832548 | 0.88 | HTR6 (0.39) | HSD11B1TSHRHTR6 | |
| SCHEMBL9833895 | 0.86 | ACLY (0.41) | HSD11B1TSHRKMT2A | |
| SCHEMBL9831338 | 0.86 | TSHR (0.34) | HSD11B1TSHRALDH1A1HTR6 | |
| SCHEMBL9830400 | 0.86 | ALDH1A1 (0.36) | TSHRALDH1A1HTR6 | |
| SCHEMBL9832538 | 0.86 | TSHR (0.38) | TSHRALDH1A1KMT2ASMN1; SMN2HTR6 | |
| SCHEMBL9831362 | 0.86 | TSHR (0.38) | TSHRALDH1A1KMT2ASMN1; SMN2HTR6 | |
| SCHEMBL9832408 | 0.85 | HSD11B1 (0.36) | HSD11B1TSHRALDH1A1L3MBTL1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011761-A1 | REDUCING PESTICIDAL INTERACTIONS IN CROPS | MONSANTO COMPANY (US) | 1992-07-23 | — | — | WO | claimed |
| WO-1992010098-A1 | SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS | MONSANTO COMPANY (US) | 1992-06-25 | — | — | WO | claimed |
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |
| US-4954163-A | PRE-AND POSTEMERGENCE HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1990-09-04 | — | — | US | claimed |
| US-4818273-A | Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides | THE DOW CHEMICAL COMPANY (US) | 1989-04-04 | — | — | US | claimed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| US-5880066-A | COMPOSITION COMPRISING TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE AND OXAZOLIDINE DICHLOROACETAMIDE ANTIDOTE | MONSANTO COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| EP-0565593-B1 | REDUCING PESTICIDAL INTERACTIONS IN CROPS | MONSANTO CO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5484760-A | AMIDES | MONSANTO COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| WO-1992011761-A1 | REDUCING PESTICIDAL INTERACTIONS IN CROPS | MONSANTO COMPANY (US) | 1992-07-23 | — | — | WO | disclosed |
| WO-1992010098-A1 | SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS | MONSANTO COMPANY (US) | 1992-06-25 | — | — | WO | disclosed |
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4983772-A | 2-Methoxy-6-trifluoromethylaniline and 2,6-difluoro-3-methylaniline, intermediates to triazolo/1,5-a/pyrmidine-2-sulfonamide herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-01-08 | — | — | US | disclosed |
| US-4886883-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0330137-A1 | Intermediate compounds for the preparation of 1,2,4-triazolo [1,5-a]pyrimidine-2-sulfonamides | DowElanco (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4818273-A | Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides | THE DOW CHEMICAL COMPANY (US) | 1989-04-04 | — | — | US | disclosed |
| US-4755212-A | Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4741764-A | SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL | THE DOW CHEMICAL COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |