Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.57 |
| ▸ | BACE1 | P56817 | 7/20 | 0.57 |
| ▸ | BCHE | P06276 | 5/20 | 0.57 |
| ▸ | VCP | P55072 | 3/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837850 | 0.94 | VCP (0.60) | ACHEBACE1BCHEVCPKDM1A | |
| SCHEMBL7841536 | 0.89 | ACHE (0.66) | ACHEBACE1BCHEVCPMEN1 | |
| SCHEMBL22815725 | 0.82 | ACHE (0.70) | ACHEBACE1BCHEVCPMEN1 | |
| SCHEMBL13573605 | 0.81 | ACHE (0.55) | ACHEBACE1BCHEVCPMEN1 | |
| SCHEMBL3958384 | 0.79 | DRD4 (0.56) | ACHEBACE1BCHEVCPMEN1 | |
| SCHEMBL803329 | 0.78 | ITGB3 (0.49) | VCPKDM1AMAOBITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL785765 | 0.77 | ITGB3 (0.48) | VCPKDM1AMAOBITGB3ITGA2B | |
| SCHEMBL7839245 | 0.76 | VCP (0.59) | ACHEBACE1BCHEVCPKDM1A | |
| SCHEMBL11378018 | 0.76 | ACHE (0.50) | ACHEBACE1BCHEVCPKDM1A | |
| SCHEMBL7014966 | 0.76 | ITGB3 (0.52) | VCPMEN1KMT2AGRIN2BITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |