Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018201 | 0.75 | CRHR1 (0.34) | MEN1KMT2A | |
| SCHEMBL3070666 | 0.67 | HSD17B10 (0.70) | HSD17B10RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24728110 | 0.66 | CRHR1 (0.33) | — | |
| SCHEMBL4856417 | 0.66 | CRHR1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL24727888 | 0.66 | ADORA2A (0.40) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9507522 | 0.66 | CRHR1 (0.33) | — | |
| SCHEMBL13752162 | 0.66 | RAB9A (0.70) | HSD17B10RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24728111 | 0.65 | CRHR1 (0.32) | SMN1; SMN2MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL11120077 | 0.64 | PDE4A (0.50) | HSD17B10RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11163114 | 0.63 | ALDH1A1 (0.40) | HSD17B10RAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5904738-A | Gas-fade inhibition | CROMPTON & KNOWLES CORPORATION (US) | 1999-05-18 | — | — | US | disclosed |