Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356687 | 0.86 | HTR7 (0.36) | F10ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL8355474 | 0.86 | ITGB3 (0.38) | F10ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL8352568 | 0.86 | S1PR5 (0.37) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8352849 | 0.82 | ITGB3 (0.39) | F10ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL8357014 | 0.79 | LSS (0.39) | F10ITGB3ITGA2B | |
| SCHEMBL8349143 | 0.77 | NOTUM (0.41) | F10ITGB3ITGA2BF2 | |
| SCHEMBL8356607 | 0.77 | HRH3 (0.36) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8352050 | 0.77 | ALDH1A1 (0.35) | F10ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL8592389 | 0.76 | HRH3 (0.38) | ITGB3ITGA2BDRD4SLC6A4HTR7 | |
| SCHEMBL8592465 | 0.75 | HRH3 (0.38) | ITGB3ITGA2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |