Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 5/20 | 0.54 |
| ▸ | TACR1 | P25103 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350132 | 0.86 | TACR2 (0.53) | TACR2TACR1TSHRHTT | |
| SCHEMBL8355501 | 0.85 | TACR2 (0.51) | TACR2TACR1KMT2AMEN1 | |
| SCHEMBL8347206 | 0.81 | TACR2 (0.51) | TACR2TACR1 | |
| SCHEMBL8347396 | 0.80 | TACR2 (0.48) | TACR2TACR1CYP2C19 | |
| SCHEMBL8350232 | 0.80 | TACR2 (0.52) | TACR2TACR1KMT2AALDH1A1LMNA | |
| SCHEMBL8348494 | 0.79 | TACR2 (0.50) | TACR2TACR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8349962 | 0.79 | TACR2 (0.50) | TACR2TACR1ALDH1A1TSHR | |
| SCHEMBL8355522 | 0.79 | TACR2 (0.53) | TACR2TACR1ALDH1A1LMNA | |
| SCHEMBL8808293 | 0.79 | TACR2 (0.65) | TACR2TACR1KMT2AMEN1 | |
| SCHEMBL8636699 | 0.78 | SPR (0.40) | TACR2TACR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861416-A | TREATMENT OF ASTHMA OR COUGH | MERRELL PHARMACEUTICALS INC. (US) | 1999-01-19 | — | — | US | disclosed |
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |