SCHEMBL8356166

SCHEMBL8356166

CC(C)C(=O)O.COc1ccc(C=O)c(OC)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.75
MAPT P10636 4/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
CYP1A2 P05177 6/20 0.54
CYP1A1 P04798 5/20 0.54
CYP1B1 Q16678 5/20 0.54
TRIM24 O15164 1/20 0.54
TYR P14679 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TNFRSF1A P19438 1/20 0.51
ERN1 O75460 2/20 0.50
LY96 Q9Y6Y9 1/20 0.49
NFE2L2 Q16236 1/20 0.49
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96291 0.87 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL15329865 0.85 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2ACYP1A2
Hydrochloric Acid SCHEMBL9456784 0.85 ALDH1A1 (0.96) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL5566174 0.84 ALDH1A1 (0.80) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL5561328 0.84 ALDH1A1 (0.59) ALDH1A1MAPTMEN1KMT2ACYP1A2
Ethylene SCHEMBL4914414 0.83 ALDH1A1 (0.92) ALDH1A1MAPTMEN1KMT2ACYP1A2
Formaldehyde SCHEMBL28854145 0.83 ALDH1A1 (0.92) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL18478003 0.83 ALDH1A1 (0.67) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL3633730 0.82 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL16046208 0.82 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5973163-A CHEMICAL INTERMEDIATE FOR ANTITUMOR AGENT INDENA S.P.A. (IT) 1999-10-26 US disclosed