Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353882 | 0.81 | CYP1A2 (0.38) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8358773 | 0.73 | CNR2 (0.44) | ALOX5L3MBTL1PTGDR2KMT2ARAB9A | |
| SCHEMBL7970472 | 0.63 | SRC (0.55) | ALOX5L3MBTL1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL13777343 | 0.63 | MEN1 (0.55) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL8353820 | 0.62 | SIGMAR1 (0.43) | — | |
| SCHEMBL30306293 | 0.61 | MEN1 (0.66) | L3MBTL1SMN1; SMN2PTGDR2KMT2ANPC1 | |
| SCHEMBL5598351 | 0.59 | ALDH1A1 (0.61) | L3MBTL1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL20940489 | 0.59 | ALOX5 (1.00) | ALOX5KMT2A | |
| SCHEMBL6203601 | 0.59 | ABCB1 (0.62) | ALOX5KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28283295 | 0.59 | AKR1C3 (0.64) | ALOX5L3MBTL1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |