Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353882 | 0.89 | CYP1A2 (0.38) | CNR2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL10771271 | 0.75 | AKR1C3 (0.56) | CNR2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL8354825 | 0.74 | AKR1C3 (0.51) | CNR2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL8356247 | 0.73 | ALOX5 (0.41) | AKR1C3MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4663300 | 0.70 | AKR1C3 (0.62) | CNR2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL4377895 | 0.67 | AKR1C3 (0.57) | AKR1C3AKR1C2PTGS2 | |
| SCHEMBL8354130 | 0.67 | LMNA (0.54) | CNR2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL30306268 | 0.61 | CNR2 (1.00) | CNR2KMT2APTGS1PTGS2ALDH1A1 | |
| SCHEMBL6279940 | 0.60 | HPGD (0.56) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2955217 | 0.59 | CA2 (0.43) | MEN1KMT2ATUBB1TP53PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |