SCHEMBL8356352

SCHEMBL8356352

C=CC(=O)OCCn1sc2ccccc2c1=O

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.56
KAT2A Q92830 3/20 0.54
KAT2B Q92831 3/20 0.54
FAAH O00519 1/20 0.49
MGLL Q99685 1/20 0.49
G6PD P11413 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13863957 0.76 KDM4E (0.62)
SCHEMBL11278746 0.76 CASP3 (0.74) CASP3KAT2AKAT2BFAAHMGLL
SCHEMBL20022714 0.76 CASP3 (0.63) CASP3KAT2AKAT2BFAAHMGLL
SCHEMBL8356552 0.74 CASP3 (0.66) CASP3KAT2AKAT2BFAAHMGLL
SCHEMBL24836229 0.73 FAAH (0.76) CASP3KAT2AKAT2BFAAHMGLL
SCHEMBL24836231 0.73 FAAH (0.81) CASP3KAT2AKAT2BFAAHMGLL
SCHEMBL24836228 0.72 FAAH (0.84) CASP3KAT2AKAT2BFAAHMGLL
SCHEMBL29697308 0.72 FNTA (0.51)
SCHEMBL378868 0.72 FNTA (0.51)
SCHEMBL9274624 0.71 KAT2A (0.66) CASP3KAT2AKAT2BG6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11116559-A None JP disclosed
JP-H11116559-A ISOTHIAZOLE DERIVATIVE AND ITS PRODUCTION SUMITOMO SEIKA CHEM CO LTD 1999-04-27 JP disclosed