Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358212 | 0.86 | SLC27A1 (0.62) | ALDH1A1LMNATSHRSLC27A1BCHE | |
| SCHEMBL8354101 | 0.80 | SLC27A1 (0.66) | ALDH1A1LMNAKDM4EDRD2DRD3 | |
| SCHEMBL8358040 | 0.79 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4ETSHRHSD17B10 | |
| SCHEMBL27927214 | 0.78 | LMNA (0.52) | ALDH1A1LMNATSHRL3MBTL1SLC27A1 | |
| SCHEMBL8353817 | 0.77 | ALDH1A1 (0.70) | ALDH1A1LMNAKDM4EDRD2DRD3 | |
| SCHEMBL29057509 | 0.75 | OGA (0.48) | ALDH1A1LMNABCHEMEN1KMT2A | |
| SCHEMBL27008691 | 0.74 | OGA (0.66) | LMNAKMT2A | |
| SCHEMBL4861743 | 0.73 | GAA (0.62) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL9332450 | 0.73 | GAA (0.62) | ALDH1A1LMNAKDM4ETSHRMEN1 | |
| SCHEMBL8351069 | 0.73 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |