SCHEMBL8356513

SCHEMBL8356513

NC(=O)Cc1ccc(CC(=O)N(C2CCCCC2)C2CCCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
CA2 P00918 1/20 0.46
S1PR1 P21453 1/20 0.44
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
CCR5 P51681 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8356511 0.92 KMT2A (0.60) KMT2AMEN1S1PR1ALDH1A1POLB
SCHEMBL31757297 0.90 KMT2A (0.45) KMT2AMEN1S1PR1ALDH1A1POLB
SCHEMBL9256455 0.88 L3MBTL1 (0.44) KMT2AMEN1S1PR1ALDH1A1POLB
SCHEMBL8356508 0.85 KMT2A (0.55) KMT2AMEN1CA2S1PR1ALDH1A1
SCHEMBL29116794 0.83 L3MBTL1 (0.57) KMT2AMEN1ALDH1A1MAPK1CCR5
SCHEMBL7941807 0.75 CA2 (0.50) KMT2ACA2L3MBTL1
SCHEMBL16299033 0.74 MEN1 (0.77) KMT2AMEN1ALDH1A1CCR5L3MBTL1
SCHEMBL7080112 0.73 KMT2A (0.41) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL14297341 0.73 NPC1 (0.55) KMT2AMEN1S1PR1ALDH1A1POLB
SCHEMBL2575803 0.72 MEN1 (0.51) KMT2AMEN1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5973076-A MOLDING; CONTROLLING TEMPERATURE IN PRESENCE OF AN AMIDE COMPOUND NEW JAPAN CHEMICAL CO., LTD. (JP) 1999-10-26 US claimed
EP-0776933-B1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEM CO LTD (JP) 1999-08-04 EP claimed
EP-0776933-A1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEMICAL CO.,LTD. (JP) 1997-06-04 EP claimed
US-5973076-A MOLDING; CONTROLLING TEMPERATURE IN PRESENCE OF AN AMIDE COMPOUND NEW JAPAN CHEMICAL CO., LTD. (JP) 1999-10-26 US disclosed
EP-0776933-B1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEM CO LTD (JP) 1999-08-04 EP disclosed
EP-0776933-A1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEMICAL CO.,LTD. (JP) 1997-06-04 EP disclosed