Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480957 | 0.91 | CA2 (0.55) | CA2 | |
| SCHEMBL2649112 | 0.84 | HAO1 (0.53) | CA2RORCHAO1HTR2CHTR2B | |
| SCHEMBL11674678 | 0.84 | HAO1 (0.53) | CA2RORCHAO1HTR2CHTR2B | |
| SCHEMBL2634975 | 0.83 | ESR2 (0.56) | CA2HRH3 | |
| SCHEMBL9751108 | 0.82 | RORC (0.52) | RORCHAO1HTR2CHTR2BHDAC1 | |
| SCHEMBL3289619 | 0.79 | HTT (0.55) | CA2RORCHAO1HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL30519937 | 0.79 | HTR3A (0.50) | — | |
| SCHEMBL1089454 | 0.78 | HAO1 (0.51) | RORCHAO1HTR2CHTR2BHDAC1 | |
| SCHEMBL11564250 | 0.78 | RORC (0.52) | RORCHAO1HTR2CHTR2BHDAC1 | |
| SCHEMBL11674790 | 0.78 | RORC (0.52) | RORCHAO1HTR2CHTR2BHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245817-B1 | NEUROPEPTIDE Y | BAYER CORPORATION | 2001-06-12 | — | — | US | disclosed |
| US-6048900-A | FOR TREATING EATING DISORDERS, INSULIN RESISTANT DIABETES, HYPERTENSION, HYPERLIPEMIA | BAYER CORPORATION (US) | 2000-04-11 | — | — | US | disclosed |
| US-3968142-A | ANALGESIC, ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |