Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356592 | 0.80 | PARP15 (0.57) | PARP15PARP10 | |
| SCHEMBL31268338 | 0.78 | PARP15 (0.56) | PARP15PARP10 | |
| SCHEMBL10533845 | 0.78 | PARP15 (0.56) | PARP15PARP10 | |
| SCHEMBL11937133 | 0.74 | KMT2A (0.60) | ALDH1A1MAPTHTTSMN1; SMN2PARP15 | |
| SCHEMBL28729859 | 0.73 | VCP (0.38) | VCPMETAP2METAP1ALDH1A1MAPT | |
| SCHEMBL18616178 | 0.72 | LTA4H (0.62) | ALDH1A1MAPTALOX12HTTSMN1; SMN2 | |
| SCHEMBL28653078 | 0.72 | VCP (0.35) | VCPMETAP2METAP1ALDH1A1MAPT | |
| SCHEMBL20472563 | 0.72 | OPRM1 (0.41) | — | |
| SCHEMBL11682621 | 0.71 | CTSL (0.41) | PARP15PARP10 | |
| SCHEMBL726735 | 0.71 | TDP1 (0.66) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11228570-A | — | — | None | — | — | JP | disclosed |
| JP-H11228570-A | 5-(SUBSTITUTED PHENYL)-4-(3-INDOLYL)IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1999-08-24 | — | — | JP | disclosed |